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Precision Medicine Bioinformatics: From raw genome and transcriptome data to clinical interpretation (PMBI01)

29 October 2018 - 2 November 2018

£275.00 - £550

Course Overview:

Precision medicine refers to the use of prevention and treatment strategies that are tailored to the unique features of each individual and their disease. Analysis of high throughput genome and transcriptome data is major component of new large-scale precision medicine efforts. This analysis involves the identification of specific genome or transcriptome features that predispose an individual to disease, predict response to specific therapy, or influence diagnosis and prognosis. During this course (PMBI01), students will perform an end-to-end precision medicine analysis of real human genome (WGS and Exome) and transcriptome (RNA-seq) data. Students will start with raw sequence data for a hypothetical patient, learn to use the tools needed to analyze this data on the cloud, and interpret results in a clinical context. The goal of the analysis will be to identify personalized therapeutic options for this patient as well as identifying any prognostic or diagnostic implications in the data. After completing the course, students should be in a position to (1) understand raw sequence data formats, (2) perform bioinformatics analyses on the cloud, (3) run complete analysis pipelines for alignment, variant calling, annotation, and RNA-seq, (4) visualize and interpret whole genome, exome and RNA-seq results, (5) leverage the identification of passenger variants for immunotherapy (e.g. personalized cancer vaccines) and disease monitoring applications, and (6) begin to place these results in a clinical context by use of variant knowledgebases. The data, tools, and analysis will be most directly relevant to human cancer genomics and bioinformatics. However, many of the skills and concepts covered will be applicable to other human diseases and even those studying non-human organisms. All course materials (including copies of presentations, practical exercises, data files, and example scripts prepared by the instructing team) will be provided electronically to participants.

Intended Audience

This workshop is primarily aimed at researchers and technical workers with a background in biology who want to learn fundamental bioinformatics skills for genomics with a particular emphasis on medical research applications. The course is essentially a crash course in bioinformatics for next generation sequence data analysis. It would also be useful for students with a computational background who seek an introduction to genomics technology and analysis approaches. In general, it is suitable for anyone working with genome or transcriptome data in the context of disease research. Attendees are encouraged to bring their own data or project outlines for discussion. Some time during the course will be dedicated to consultation with a team of instructors from the McDonnell Genome Institute.

Venue –   PR informatics head office, 53 Morrison Street, Glasgow, G5 8LB – Google map
Availability – 30 places
Duration – 5 days
Contact hours – Approx. 37 hours
ECT’s – Equal to 3 ECT’s
Language – English


• COURSE ONLY – Includes lunch and refreshments.
• ACCOMMODATION PACKAGE (to be purchased in addition to the course only option) – Includes breakfast, lunch, welcome dinner Monday evening, farewell dinner Thursday evening, refreshments and accommodation. Self-catering facilities are available in the accommodation. Accommodation is approximately a 6-minute walk from the PR informatics head office. Accommodation is multiple occupancy (max 3-4 people) single sex en-suite rooms. Arrival Sunday 20th May (after 5pm) and departure Friday 25th May (accommodation must be vacated by 9am). An additional nights accommodation can be purchased, departure 9am Saturday morning email for details.

To book ‘COURSE ONLY’ with the option to add the additional ‘ACCOMMODATION PACKAGE’ please scroll to the bottom of this page.

Other payment options are available please email oliverhooker@prinformatics.com

Cancellation policy: Cancellations are accepted up to 28 days before the course start date subject to a 25% cancellation fee. Cancellations later than this may be considered, contact oliverhooker@prinformatics.com Failure to attend will result in the full cost of the course being charged. In the unfortunate event that PRinformatics must cancel this course due to unforeseen circumstances a full refund for the course will be credited. However PRinformatics cannot be held responsible for any travel fees, accommodation or other expenses incurred to you as a result of the cancellation.



Dr. Malachi Griffith


Dr. Obi Griffith

Teaching Format
Course Programme


29 October 2018
2 November 2018
£275.00 - £550


PR informatics head office
53 Morrison Street
Glasgow, Scotland G5 8LB United Kingdom
+ Google Map


24 available
PMBI01 ' COURSE ONLY'£550.00‘COURSE ONLY’ £550.00 Places 1-24
24 available